What it is: An LDL cholesterol test measures low-density lipoprotein cholesterol, often called "bad" cholesterol, as part of a lipid panel.
Why it's ordered: Ordered as part of routine or follow-up cardiovascular risk screening, typically alongside HDL, total cholesterol, and triglycerides.
What it detects: LDL is the main cholesterol carrier responsible for plaque buildup in artery walls, so elevated LDL is directly associated with higher cardiovascular disease risk.
Collection & prep: A standard blood draw from a vein in the arm as part of a lipid panel; some labs request 9–12 hours of fasting, particularly if triglycerides are very high, since that affects the LDL calculation.
Results:
Below 100 mg/dL – optimal for most people (below 70 mg/dL for those with diabetes)
Above target range – classified as borderline, intermediate, or high cardiovascular risk depending on the level
Possible complications of high LDL: Sustained high LDL contributes to atherosclerosis and raises the risk of heart attack and stroke; treatment targets vary based on a person's overall cardiovascular risk profile, not LDL alone.
Statements made in the Clinical Manual have not been evaluated by the FDA. The products mentioned are not intended to diagnose, treat, cure or prevent any disease.
